Every time we care for a single person we make the whole world better...

A photo of a little girl smiling in the sunshine.

At Pierre Fabre Pharmaceuticals Inc., our mission is to deliver breakthrough therapies to US patient populations with high unmet needs

and limited treatment options. We focus on oncology and rare diseases. We strive to bring meaningful therapeutic innovation to patients in need, no matter how rare their disease might be.

Our innovation aspiration

At Pierre Fabre Pharmaceuticals, we are building a company where innovation is rooted in partnership and mutual purpose: to improve the lives of people living with cancer and rare diseases. That means healthcare professionals are our trusted partners, science and nature are our sources of inspiration, and long-term relationships with researchers fuel our innovation.

A photo of scientists working with a microscope.
A photo of two people hugging in a park.

Our patient-centric commitment

We help patients live better by designing and developing therapeutic solutions. We build and nurture strong relationships with patients, caregivers, and patient organizations and collaborate with them to create best-in-class patient education and programs. We capture real-world evidence in all our indications, so we better understand how our medicines affect a broader set of patients. By keeping the patient voice front and center, we address the areas of highest unmet need and focus on delivering long-term value for patients.

Our parent company

We are the US pharmaceutical subsidiary of Pierre Fabre Laboratories. A global healthcare company for more than 60 years, Pierre Fabre Laboratories operates in 43 countries, with more than 10,000 employees and over $3 billion in revenue. The medical care division focuses on oncology, dermatology, rare diseases, primary care, and family health.

Pierre Fabre Laboratories is a purpose-driven company that strives to benefit society as a whole, encompassing healthcare, pharmaceutical ethics, and climate transition. Our focus on long-term value stems from our unique ownership structure: the company's majority shareholder is the Pierre Fabre Foundation, a government-recognized public-interest foundation that works to improve access to quality medicines and healthcare in Africa and Southeast Asia.

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Our purpose

Every time we innovate to help each person live better...
Every time we repay nature for her treasures...
Every time we share the fruit of our efforts with those working and living beside us...
Every time the Pierre Fabre Foundation improves access to healthcare for those most in need...

Every time we care for a single person, we make the whole world better...

Partnerships and Pipeline

Every time we innovate to help each person live better...

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Our ambition is to be a partner of choice for biotechs bringing innovative therapies to market.

Our focus is breakthrough therapies for diseases with high unmet needs, especially in oncology and rare diseases. We are actively identifying potential therapies to in-license and complement our growing pipeline.

As part of Pierre Fabre Laboratories, we bring six decades of worldwide experience in pharmaceutical commercialization, while our agile corporate structure enables us to develop and implement at biotech speed. Most of all, we emphasize creating long-term value for patients and society.

Innovative precision treatments

We build our pipeline through both research and development (R&D) and business development and licensing (BD&L). In both domains, oncology is a priority focus, accounting for over 80% of total investment.

Our current portfolio consists of one commercial product, one product in FDA review, one product in Phase II development, and two products in Phase I development.

Disease Area:
Dermatology

Indication:
Proliferating infantile hemangioma requiring systemic therapy

  • Beta-blocker
  • Blocks beta-adrenergic receptors
  • Administered as an oral solution
  • Received FDA Approval in March 2014

Development Partner:
Centre Hospitalier Universitaire Bordeaux

Approved

Development
Partner:

Centre Hospitalier Universitaire Bordeaux

Tabelecleucel

Disease Area:
Hematology

Indication:
Relapsed or refractory Epstein-Barr virus+ post-transplant lymphoproliferative disorder (EBV+ PTLD)

  • Cell therapy
  • Allogeneic T-cell therapy where immune cells from a healthy donor are used to target and destroy EBV-infected B cells
  • Administered through IV Injection
  • Biologics license application (BLA) submitted to FDA in May 2024
  • Clinicaltrials.gov ID: NCT03394365

Development Partner:
Atara Bio

Registration

Development
Partner:

Atara Bio

ER004

Disease Area:
Genetic Disorder

Indication:
Hypohidrotic ectodermal dysplasia (XLHED)

  • Protein replacement therapy
  • In-utero therapy designed to replace the function of endogenous ectodysplasin A1 (EDA1), which is a protein key to the normal development of ectodermal structures in fetuses
  • Administered through intra-amniotic injection
  • First patient enrolled in the Edelife trial in April 2022
  • Clinicaltrials.gov ID: NCT04980638

Development Partner:
EspeRare

Phase II

Development
Partner:

EspeRare

Exarafenib

Disease Area:
Solid Tumor

Indication:
NRAS mutant melanoma

  • Targeted therapy
  • Pan-RAF small molecule inhibitor that targets BRAF class I, II, and III and NRAS alterations, which are known drivers of disease in patients with melanoma
  • Administered orally
  • First patient enrolled in August 2021
  • Pierre Fabre and Kinnate entered into an Asset Purchase Agreement for Exarafenib in March 2024
  • Clinicaltrials.gov ID: NCT04913285

Development Partner:
Kinnate Biopharma

Phase I

Development
Partner:

Kinnate Biopharma

PFL-002 / VERT-002

Disease Area:
Solid Tumor

Indication:
Non-small cell lung cancer (NSCLC) with mutation or amplification of MET

  • Targeted therapy
  • Monoclonal antibody acting as a degrader of c-MET, which is a known driver of disease in patients with MET mutations or amplification in NSCLC
  • Investigational New Drug (IND) application filed to the FDA in June 2024
  • First patient enrolled in October 2024

Phase I

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Leadership

Experienced Leadership for Bold Pursuits

A group photo of the Pierre Fabre Pharmaceuticals cell therapy leadership team, from October 2024.

Pierre Fabre Pharmaceuticals boasts a seasoned leadership team with significant oncology and rare-disease knowledge.

Collectively, we bring a strong track record in development, operations, and commercialization, across multiple platforms including biologics, targeted therapies, and cell therapies. We work together to channel our experience and make a difference for patients.

Headshot of Adriana Herrera

Adriana
Herrera

Chief Executive Officer

Headshot of Aisha Babar

Aisha
Babar

General Counsel and Compliance Officer

Headshot of Lara Cavalli

Lara
Cavalli

Medical Affairs

Headshot of Olivier Delannoy

Olivier
Delannoy

Mature Brands

Headshot of Adam Fenimore

Adam
Fenimore

Technical Operations

Headshot of Ilya Ganov

Ilya
Ganov

Finance

Headshot of Arthur Ginies

Arthur
Ginies

Business Operations

Headshot of Seung Hyun Moon

Seung
Hyun Moon

Commercial and Business Development

Headshot of Joshua Sammon

Joshua
Sammon

Value and Access

Headshot of Antonio Trejo-Diaz

Antonio
Trejo Diaz

Regulatory Affairs and Pharmacovigilance

Headshot of Elizabeth Turcotte

Elizabeth
Turcotte

Patient Affairs

News

Press Releases

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Tabelecleucel

Updated results of Phase III ALLELE Study presented at ASH annual meeting confirm efficacy, safety, and durability of novel allogeneic cell therapy Tabelecleucel in relapsed or refractory Epstein-Barr virus-positive post-transplant lymphoproliferative disease (EBV+ PTLD)

07 December 2024

PFL-002 / VERT-002

Pierre Fabre Laboratories announce first patient dosed in Phase I/II clinical trial of PFL-002/VERT-002, an innovative targeted therapy intended to treat non-small cell lung cancer with MET alterations

24 October 2024

Tabelecleucel

Pierre Fabre Laboratories announces the submission by Atara Biotherapeutics of Tabelecleucel Biologics License Application for treatment of Epstein-Barr virus-positive post-transplant lymphoproliferative disease with U.S. FDA

20 May 2024

Exarafenib

Kinnate Biopharma Inc. sells its investigational pan-RAF inhibitor, Exarafenib, to Pierre Fabre Laboratories

1 March 2024

Tabelecleucel

Atara Biotherapeutics and Pierre Fabre Laboratories announce publication of Phase III ALLELE Tabelecleucel Data in The Lancet Oncology

31 January 2024

Pierre Fabre

Foundation Medicine announces collaboration with Pierre Fabre Laboratories to develop companion diagnostics in non-small cell lung cancer

15 November 2023

Tabelecleucel

Pierre Fabre Laboratories to accelerate their development in onco-hematology by acquiring the license for a breakthrough T-cell immunotherapy in North America

3 November 2023

Pierre Fabre

Pierre Fabre Laboratories and Vernalis announce a drug discovery collaboration in oncology

25 September 2023

PFL-002 / VERT-002

Pierre Fabre Laboratories acquires Vertical Bio and its innovative targeted therapy candidate for patients suffering from non-small cell lung cancer with MET alteration

12 September 2023

ER004

Pierre Fabre and the EspeRare Foundation start the EDELIFE clinical trial of a prenatal treatment for a rare genetic disease, XLHED

15 November 2021